Human KDM4A activation kit by CRISPRa

CAT#: GA106494

KDM4A CRISPRa kit - CRISPR gene activation of human lysine demethylase 4A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KDM4A
• Locus ID: 9682
• Kit Components:

  GA106494G1, KDM4A gRNA vector 1 in pCas-Guide-CRISPRa

  GA106494G2, KDM4A gRNA vector 2 in pCas-Guide-CRISPRa

  GA106494G3, KDM4A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014663
• Synonyms: JHDM3A; JMJD2; JMJD2A; TDRD14A
• Summary: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]