Human GPRASP1 activation kit by CRISPRa

CAT#: GA106545

GPRASP1 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor associated sorting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPRASP1
• Locus ID: 9737
• Kit Components:

  GA106545G1, GPRASP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106545G2, GPRASP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106545G3, GPRASP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099410, NM_001099411, NM_001184727, NM_014710
• Synonyms: GASP; GASP-1; GASP1
• Summary: This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]