Human RNF144 (RNF144A) activation kit by CRISPRa

CAT#: GA106584

RNF144A CRISPRa kit - CRISPR gene activation of human ring finger protein 144A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RNF144A
• Locus ID: 9781
• Kit Components:

  GA106584G1, RNF144A gRNA vector 1 in pCas-Guide-CRISPRa

  GA106584G2, RNF144A gRNA vector 2 in pCas-Guide-CRISPRa

  GA106584G3, RNF144A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014746, NM_001349181, NM_001349182, NM_001349183, NM_001349184, NM_001349185, NM_001349186, NR_146069
• Synonyms: RNF144; UBCE7IP4
• Summary: This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017]