Human Matrin 3 (MATR3) activation kit by CRISPRa

CAT#: GA106585

MATR3 CRISPRa kit - CRISPR gene activation of human matrin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MATR3
• Locus ID: 9782
• Kit Components:

  GA106585G1, MATR3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106585G2, MATR3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106585G3, MATR3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001194954, NM_001194955, NM_001194956, NM_001282278, NM_018834, NM_199189, NR_036535
• Synonyms: ALS21; MPD2; VCPDM
• Summary: This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013]