Human PTDSS1 activation kit by CRISPRa

CAT#: GA106594

PTDSS1 CRISPRa kit - CRISPR gene activation of human phosphatidylserine synthase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTDSS1
• Locus ID: 9791
• Kit Components:

  GA106594G1, PTDSS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106594G2, PTDSS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106594G3, PTDSS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290225, NM_014754
• Synonyms: LMHD; PSS1; PSSA
• Summary: The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]