Human DAZAP2 activation kit by CRISPRa

CAT#: GA106602

DAZAP2 CRISPRa kit - CRISPR gene activation of human DAZ associated protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DAZAP2
• Locus ID: 9802
• Kit Components:

  GA106602G1, DAZAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106602G2, DAZAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106602G3, DAZAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136264, NM_001136266, NM_001136267, NM_001136268, NM_001136269, NM_014764
• Synonyms: PRTB
• Summary: This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]