Human NUPL1 (NUP58) activation kit by CRISPRa

CAT#: GA106615

NUP58 CRISPRa kit - CRISPR gene activation of human nucleoporin 58

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUP58
• Locus ID: 9818
• Kit Components:

  GA106615G1, NUP58 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106615G2, NUP58 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106615G3, NUP58 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008564, NM_001008565, NM_014089, NM_014778
• Synonyms: NUP45; NUPL1; PRO2463
• Summary: This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]