Human ELMO1 activation kit by CRISPRa

CAT#: GA106637

ELMO1 CRISPRa kit - CRISPR gene activation of human engulfment and cell motility 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELMO1
• Locus ID: 9844
• Kit Components:

  GA106637G1, ELMO1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106637G2, ELMO1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106637G3, ELMO1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039459, NM_001206480, NM_001206482, NM_014800, NM_130442, NR_038120, NR_038121
• Synonyms: CED-12; CED12; ELMO-1
• Summary: This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]