Human CAP350 (CEP350) activation kit by CRISPRa

CAT#: GA106648

CEP350 CRISPRa kit - CRISPR gene activation of human centrosomal protein 350

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEP350
• Locus ID: 9857
• Kit Components:

  GA106648G1, CEP350 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106648G2, CEP350 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106648G3, CEP350 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014810
• Synonyms: CAP350; GM133
• Summary: The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]