Human AIP1 (MAGI2) activation kit by CRISPRa

CAT#: GA106654

MAGI2 CRISPRa kit - CRISPR gene activation of human membrane associated guanylate kinase, WW and PDZ domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAGI2
• Locus ID: 9863
• Kit Components:

  GA106654G1, MAGI2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106654G2, MAGI2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106654G3, MAGI2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301128, NM_012301
• Synonyms: ACVRIP1; AIP-1; AIP1; ARIP1; MAGI-2; SSCAM
• Summary: The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]