Human POM121 activation kit by CRISPRa

CAT#: GA106671

POM121 CRISPRa kit - CRISPR gene activation of human POM121 transmembrane nucleoporin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POM121
• Locus ID: 9883
• Kit Components:

  GA106671G1, POM121 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106671G2, POM121 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106671G3, POM121 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001257190, NM_014833, NM_172020, NM_001367610
• Synonyms: P145; POM121A
• Summary: This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]