Human MRC2 activation kit by CRISPRa

CAT#: GA106688

MRC2 CRISPRa kit - CRISPR gene activation of human mannose receptor C type 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MRC2
• Locus ID: 9902
• Kit Components:

  GA106688G1, MRC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106688G2, MRC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106688G3, MRC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006039
• Synonyms: CD280; CLEC13E; ENDO180; UPARAP
• Summary: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]