Human AMMECR1 activation kit by CRISPRa

CAT#: GA106731

AMMECR1 CRISPRa kit - CRISPR gene activation of human Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMMECR1
• Locus ID: 9949
• Kit Components:

  GA106731G1, AMMECR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106731G2, AMMECR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106731G3, AMMECR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025580, NM_001171689, NM_015365
• Synonyms: AMMERC1
• Summary: The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]