Human HS3ST3A1 activation kit by CRISPRa

CAT#: GA106735

HS3ST3A1 CRISPRa kit - CRISPR gene activation of human heparan sulfate-glucosamine 3-sulfotransferase 3A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HS3ST3A1
• Locus ID: 9955
• Kit Components:

  GA106735G1, HS3ST3A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106735G2, HS3ST3A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106735G3, HS3ST3A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006042
• Synonyms: 3-OST-3A; 3OST3A1
• Summary: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Dec 2014]