Human HS3ST1 activation kit by CRISPRa

CAT#: GA106737

HS3ST1 CRISPRa kit - CRISPR gene activation of human heparan sulfate-glucosamine 3-sulfotransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HS3ST1
• Locus ID: 9957
• Kit Components:

  GA106737G1, HS3ST1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106737G2, HS3ST1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106737G3, HS3ST1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005114
• Synonyms: 3OST; 3OST1
• Summary: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]