Human USP15 activation kit by CRISPRa

CAT#: GA106738

USP15 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP15
• Locus ID: 9958
• Kit Components:

  GA106738G1, USP15 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106738G2, USP15 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106738G3, USP15 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252078, NM_001252079, NM_006313, NM_001351159, NM_001351160, NM_001351161, NM_001351162, NM_001351163, NM_001351164, NM_001351165, NM_001351166, NR_147078, NR_147079, NR_147080, NR_147081, NR_147082
• Synonyms: UNPH-2; UNPH4
• Summary: This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]