Human PP4R1 (PPP4R1) activation kit by CRISPRa

CAT#: GA106762

PPP4R1 CRISPRa kit - CRISPR gene activation of human protein phosphatase 4 regulatory subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP4R1
• Locus ID: 9989
• Kit Components:

  GA106762G1, PPP4R1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106762G2, PPP4R1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106762G3, PPP4R1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042388, NM_005134, NR_052003
• Synonyms: MEG1; PP4(Rmeg); PP4R1
• Summary: This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]