Human SCO2 activation kit by CRISPRa

CAT#: GA106768

SCO2 CRISPRa kit - CRISPR gene activation of human SCO cytochrome c oxidase assembly protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SCO2
• Locus ID: 9997
• Kit Components:

  GA106768G1, SCO2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106768G2, SCO2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106768G3, SCO2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001169109, NM_001169110, NM_001169111, NM_005138
• Synonyms: CEMCOX1; MYP6; SCO1L
• Summary: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014]