Human NR2E3 activation kit by CRISPRa

CAT#: GA106771

NR2E3 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 2 group E member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NR2E3
• Locus ID: 10002
• Kit Components:

  GA106771G1, NR2E3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106771G2, NR2E3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106771G3, NR2E3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014249, NM_016346, NM_001281446
• Synonyms: ESCS; PNR; rd7; RNR; RP37
• Summary: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]