Human DNAJB6 activation kit by CRISPRa

CAT#: GA106806

DNAJB6 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member B6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJB6
• Locus ID: 10049
• Kit Components:

  GA106806G1, DNAJB6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106806G2, DNAJB6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106806G3, DNAJB6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005494, NM_058246, NM_001363676
• Synonyms: DJ4; DnaJ; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; MRJ; MSJ-1
• Summary: This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]