Human UBA2 activation kit by CRISPRa

CAT#: GA106811

UBA2 CRISPRa kit - CRISPR gene activation of human ubiquitin like modifier activating enzyme 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBA2
• Locus ID: 10054
• Kit Components:

  GA106811G1, UBA2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106811G2, UBA2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106811G3, UBA2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005499
• Synonyms: ARX; HRIHFB2115; SAE2
• Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]). [supplied by OMIM, Mar 2010]