Human Cyclophilin F (PPIF) activation kit by CRISPRa

CAT#: GA106854

PPIF CRISPRa kit - CRISPR gene activation of human peptidylprolyl isomerase F

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPIF
• Locus ID: 10105
• Kit Components:

  GA106854G1, PPIF gRNA vector 1 in pCas-Guide-CRISPRa

  GA106854G2, PPIF gRNA vector 2 in pCas-Guide-CRISPRa

  GA106854G3, PPIF gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005729
• Synonyms: Cyp-D; CyP-M; CYP3; CypD
• Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]