Human LRPPRC activation kit by CRISPRa

CAT#: GA106872

LRPPRC CRISPRa kit - CRISPR gene activation of human leucine rich pentatricopeptide repeat containing

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LRPPRC
• Locus ID: 10128
• Kit Components:

  GA106872G1, LRPPRC gRNA vector 1 in pCas-Guide-CRISPRa

  GA106872G2, LRPPRC gRNA vector 2 in pCas-Guide-CRISPRa

  GA106872G3, LRPPRC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133259
• Synonyms: CLONE-23970; GP130; LRP130; LSFC
• Summary: This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]