Human Visfatin (NAMPT) activation kit by CRISPRa

CAT#: GA106878

NAMPT CRISPRa kit - CRISPR gene activation of human nicotinamide phosphoribosyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAMPT
• Locus ID: 10135
• Kit Components:

  GA106878G1, NAMPT gRNA vector 1 in pCas-Guide-CRISPRa

  GA106878G2, NAMPT gRNA vector 2 in pCas-Guide-CRISPRa

  GA106878G3, NAMPT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005746, NM_182790
• Synonyms: 1110035O14Rik; PBEF; PBEF1; VF; VISFATIN
• Summary: This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]