Human EBI3 activation kit by CRISPRa

CAT#: GA106889

EBI3 CRISPRa kit - CRISPR gene activation of human Epstein-Barr virus induced 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EBI3
• Locus ID: 10148
• Kit Components:

  GA106889G1, EBI3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106889G2, EBI3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106889G3, EBI3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005755
• Synonyms: IL-27B; IL27B
• Summary: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]