Human PLXNC1 activation kit by CRISPRa

CAT#: GA106894

PLXNC1 CRISPRa kit - CRISPR gene activation of human plexin C1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLXNC1
• Locus ID: 10154
• Kit Components:

  GA106894G1, PLXNC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106894G2, PLXNC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106894G3, PLXNC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005761, NR_037687
• Synonyms: CD232; PLXN-C1; VESPR
• Summary: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]