Human KAP1 (TRIM28) activation kit by CRISPRa

CAT#: GA106895

TRIM28 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 28

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIM28
• Locus ID: 10155
• Kit Components:

  GA106895G1, TRIM28 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106895G2, TRIM28 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106895G3, TRIM28 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005762
• Synonyms: KAP1; PPP1R157; RNF96; TF1B; TIF1B
• Summary: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]