Human WASF2 activation kit by CRISPRa

CAT#: GA106903

WASF2 CRISPRa kit - CRISPR gene activation of human WASP family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WASF2
• Locus ID: 10163
• Kit Components:

  GA106903G1, WASF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106903G2, WASF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106903G3, WASF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201404, NM_006990
• Synonyms: dJ393P12.2; IMD2; SCAR2; WASF4; WAVE2
• Summary: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]