Human RNF41 activation kit by CRISPRa

CAT#: GA106923

RNF41 CRISPRa kit - CRISPR gene activation of human ring finger protein 41

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RNF41
• Locus ID: 10193
• Kit Components:

  GA106923G1, RNF41 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106923G2, RNF41 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106923G3, RNF41 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242826, NM_005785, NM_194358, NM_194359, NR_040053
• Synonyms: FLRF; NRDP1; SBBI03
• Summary: This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]