Human NME6 activation kit by CRISPRa

CAT#: GA106931

NME6 CRISPRa kit - CRISPR gene activation of human NME/NM23 nucleoside diphosphate kinase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NME6
• Locus ID: 10201
• Kit Components:

  GA106931G1, NME6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106931G2, NME6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106931G3, NME6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308426, NM_001308427, NM_001308428, NM_001308430, NM_001308431, NM_001308433, NM_001308434, NM_001308435, NM_005793
• Synonyms: IPIA-ALPHA; NDK 6; NM23-H6
• Summary: Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]). [supplied by OMIM, Jul 2010]