Human KLRG1 activation kit by CRISPRa

CAT#: GA106949

KLRG1 CRISPRa kit - CRISPR gene activation of human killer cell lectin like receptor G1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLRG1
• Locus ID: 10219
• Kit Components:

  GA106949G1, KLRG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106949G2, KLRG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106949G3, KLRG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329099, NM_001329101, NM_001329102, NM_001329103, NM_005810, NR_137426, NR_137427, NR_137428
• Synonyms: 2F1; CLEC15A; MAFA; MAFA-2F1; MAFA-L; MAFA-LIKE
• Summary: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]