Human NET1 activation kit by CRISPRa

CAT#: GA106998

NET1 CRISPRa kit - CRISPR gene activation of human neuroepithelial cell transforming 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NET1
• Locus ID: 10276
• Kit Components:

  GA106998G1, NET1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106998G2, NET1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106998G3, NET1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001047160, NM_005863, NR_073040
• Synonyms: ARHGEF8; NET1A
• Summary: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]