Human TNIP1 activation kit by CRISPRa

CAT#: GA107031

TNIP1 CRISPRa kit - CRISPR gene activation of human TNFAIP3 interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNIP1
• Locus ID: 10318
• Kit Components:

  GA107031G1, TNIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107031G2, TNIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107031G3, TNIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252385, NM_001252386, NM_001252390, NM_001252391, NM_001252392, NM_001252393, NM_001258454, NM_001258455, NM_001258456, NM_006058, NM_001364486, NM_001364487
• Synonyms: ABIN-1; NAF1; nip40-1; VAN
• Summary: This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]