Human AKR1A1 activation kit by CRISPRa

CAT#: GA107039

AKR1A1 CRISPRa kit - CRISPR gene activation of human aldo-keto reductase family 1 member A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKR1A1
• Locus ID: 10327
• Kit Components:

  GA107039G1, AKR1A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107039G2, AKR1A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107039G3, AKR1A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001202413, NM_001202414, NM_006066, NM_153326
• Synonyms: ALDR1; ALR; ARM; DD3; HEL-S-6
• Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011]