Human CACNG2 activation kit by CRISPRa

CAT#: GA107065

CACNG2 CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel auxiliary subunit gamma 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNG2
• Locus ID: 10369
• Kit Components:

  GA107065G1, CACNG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107065G2, CACNG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107065G3, CACNG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006078
• Synonyms: MRD10
• Summary: The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. The AMPA subtype of ionotropic glutamate receptors are ligand gated ion channels that are typically activated by glutamate released from presynaptic neuron terminals and mediate fast neurotransmission in excitatory synapses. TARPs thus play an important role in synaptic plasticity, learning and memory. Mutations in this gene cause an autosomal dominant form of cognitive disability. [provided by RefSeq, Jul 2017]