Human beta IV Tubulin (TUBB4A) activation kit by CRISPRa

CAT#: GA107072

TUBB4A CRISPRa kit - CRISPR gene activation of human tubulin beta 4A class IVa

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TUBB4A
• Locus ID: 10382
• Kit Components:

  GA107072G1, TUBB4A gRNA vector 1 in pCas-Guide-CRISPRa

  GA107072G2, TUBB4A gRNA vector 2 in pCas-Guide-CRISPRa

  GA107072G3, TUBB4A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289123, NM_001289127, NM_001289129, NM_001289130, NM_001289131, NM_006087
• Synonyms: beta-5; DYT4; TUBB4
• Summary: This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014]