Human ST3GAL6 activation kit by CRISPRa

CAT#: GA107090

ST3GAL6 CRISPRa kit - CRISPR gene activation of human ST3 beta-galactoside alpha-2,3-sialyltransferase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ST3GAL6
• Locus ID: 10402
• Kit Components:

  GA107090G1, ST3GAL6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107090G2, ST3GAL6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107090G3, ST3GAL6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271142, NM_001271145, NM_001271146, NM_001271147, NM_001271148, NM_001323352, NM_001323353, NM_001323358, NM_001323359, NM_001323360, NM_001323362, NM_001323363, NM_001323364, NM_001323365, NM_001323366, NM_001323367, NM_001323368, NM_006100
• Synonyms: SIAT10; ST3GALVI
• Summary: The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016]