ST3GAL6 Human Gene Knockout Kit (CRISPR)

CAT#: KN405750

ST3GAL6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: ST3GAL6
• Locus ID: 10402
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001271142, NM_001271145, NM_001271146, NM_001271147, NM_001271148, NM_001323352, NM_001323353, NM_001323358, NM_001323359, NM_001323360, NM_001323362, NM_001323363, NM_001323364, NM_001323365, NM_001323366, NM_001323367, NM_001323368, NM_006100
• Synonyms: SIAT10; ST3GALVI
• Summary: The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016]