Human HE4 (WFDC2) activation kit by CRISPRa

CAT#: GA107093

WFDC2 CRISPRa kit - CRISPR gene activation of human WAP four-disulfide core domain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WFDC2
• Locus ID: 10406
• Kit Components:

  GA107093G1, WFDC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107093G2, WFDC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107093G3, WFDC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006103, NM_080733, NM_080734, NM_080735, NM_080736
• Synonyms: dJ461P17.6; EDDM4; HE4; WAP5
• Summary: This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]