Human TESK2 activation kit by CRISPRa

CAT#: GA107103

TESK2 CRISPRa kit - CRISPR gene activation of human testis associated actin remodelling kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TESK2
• Locus ID: 10420
• Kit Components:

  GA107103G1, TESK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107103G2, TESK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107103G3, TESK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007170, NM_001320800
• Synonyms: MGC29168; OTTMUSP00000010191; testis-specific kinase 2
• Summary: This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]