Human CD2BP2 activation kit by CRISPRa

CAT#: GA107104

CD2BP2 CRISPRa kit - CRISPR gene activation of human CD2 cytoplasmic tail binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD2BP2
• Locus ID: 10421
• Kit Components:

  GA107104G1, CD2BP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107104G2, CD2BP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107104G3, CD2BP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243646, NM_006110, NR_024465
• Synonyms: FWP010; LIN1; PPP1R59; Snu40; U5-52K
• Summary: This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]