Human KPC2 (UBAC1) activation kit by CRISPRa

CAT#: GA107105

UBAC1 CRISPRa kit - CRISPR gene activation of human UBA domain containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBAC1
• Locus ID: 10422
• Kit Components:

  GA107105G1, UBAC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107105G2, UBAC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107105G3, UBAC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016172
• Synonyms: GBDR1; KPC2; UBADC1
• Summary: Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. [UniProtKB/Swiss-Prot Function]