Human CDIPT activation kit by CRISPRa

CAT#: GA107106

CDIPT CRISPRa kit - CRISPR gene activation of human CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDIPT
• Locus ID: 10423
• Kit Components:

  GA107106G1, CDIPT gRNA vector 1 in pCas-Guide-CRISPRa

  GA107106G2, CDIPT gRNA vector 2 in pCas-Guide-CRISPRa

  GA107106G3, CDIPT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286585, NM_001286586, NM_006319, NM_145752
• Synonyms: PIS; PIS1
• Summary: Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]