Human ARIH2 activation kit by CRISPRa

CAT#: GA107108

ARIH2 CRISPRa kit - CRISPR gene activation of human ariadne RBR E3 ubiquitin protein ligase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARIH2
• Locus ID: 10425
• Kit Components:

  GA107108G1, ARIH2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107108G2, ARIH2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107108G3, ARIH2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317333, NM_001317334, NM_006321, NM_001349209, NM_001349210, NM_001349211, NM_001349212, NM_001349213, NM_001349214, NM_001349215, NM_001349216, NM_001349217, NM_001349218, NM_001349219, NM_001349220, NM_001349221, NM_001349222, NM_001349223, NM_001349224, NM_001349225, NM_001349226, NM_001349227, NM_001349228, NM_001349229, NM_001349230, NR_146082, NR_146083, NR_146084, NR_146085
• Synonyms: ARI2; TRIAD1
• Summary: The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]