Human IFI30 activation kit by CRISPRa

CAT#: GA107117

IFI30 CRISPRa kit - CRISPR gene activation of human IFI30 lysosomal thiol reductase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFI30
• Locus ID: 10437
• Kit Components:

  GA107117G1, IFI30 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107117G2, IFI30 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107117G3, IFI30 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006332
• Synonyms: GILT; IFI-30; IP-30; IP30
• Summary: The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. [provided by RefSeq, Jul 2008]