Human C1D activation kit by CRISPRa

CAT#: GA107118

C1D CRISPRa kit - CRISPR gene activation of human C1D nuclear receptor corepressor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C1D
• Locus ID: 10438
• Kit Components:

  GA107118G1, C1D gRNA vector 1 in pCas-Guide-CRISPRa

  GA107118G2, C1D gRNA vector 2 in pCas-Guide-CRISPRa

  GA107118G3, C1D gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190263, NM_001190265, NM_006333, NM_173177
• Synonyms: hC1D; LRP1; Rrp47; SUN-CoR; SUNCOR
• Summary: The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10. [provided by RefSeq, Jun 2010]