Human MAD2L2 activation kit by CRISPRa

CAT#: GA107135

MAD2L2 CRISPRa kit - CRISPR gene activation of human mitotic arrest deficient 2 like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAD2L2
• Locus ID: 10459
• Kit Components:

  GA107135G1, MAD2L2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107135G2, MAD2L2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107135G3, MAD2L2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127325, NM_006341
• Synonyms: MAD2B; POLZ2; REV7
• Summary: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]