Human SEC23B activation kit by CRISPRa

CAT#: GA107158

SEC23B CRISPRa kit - CRISPR gene activation of human SEC23 homolog B, coat complex II component

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEC23B
• Locus ID: 10483
• Kit Components:

  GA107158G1, SEC23B gRNA vector 1 in pCas-Guide-CRISPRa

  GA107158G2, SEC23B gRNA vector 2 in pCas-Guide-CRISPRa

  GA107158G3, SEC23B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172745, NM_001172746, NM_006363, NM_032985, NM_032986
• Synonyms: CDA-II; CDAII; CDAN2; HEMPAS
• Summary: The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]