Human SEC23 (SEC23A) activation kit by CRISPRa

CAT#: GA107159

SEC23A CRISPRa kit - CRISPR gene activation of human Sec23 homolog A, coat complex II component

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEC23A
• Locus ID: 10484
• Kit Components:

  GA107159G1, SEC23A gRNA vector 1 in pCas-Guide-CRISPRa

  GA107159G2, SEC23A gRNA vector 2 in pCas-Guide-CRISPRa

  GA107159G3, SEC23A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006364
• Synonyms: CLSD
• Summary: The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]