Human VTI1B activation kit by CRISPRa

CAT#: GA107165

VTI1B CRISPRa kit - CRISPR gene activation of human vesicle transport through interaction with t-SNAREs 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VTI1B
• Locus ID: 10490
• Kit Components:

  GA107165G1, VTI1B gRNA vector 1 in pCas-Guide-CRISPRa

  GA107165G2, VTI1B gRNA vector 2 in pCas-Guide-CRISPRa

  GA107165G3, VTI1B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006370
• Synonyms: v-SNARE; VTI1; VTI1-LIKE; vti1-rp1; VTI1L; VTI2
• Summary: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. [UniProtKB/Swiss-Prot Function]